Longitudinal Cohort

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Parental Obesity and the Adult Offspring’s Risk of Metabolic Dysfunction Associated Steatotic Liver Disease: Insights from a UK Birth Cohort Study

This UK cohort study reveals that both maternal and paternal obesity before pregnancy significantly increase offspring’s risk of metabolic dysfunction associated steatotic liver disease (MASLD) by age 24, largely mediated by excess ch

Sep 17, 2026Sign in to read

Neurology

Seizure Burden Falls Over Time in Treatment‑Resistant Focal Epilepsy: Implications for Interpreting Open‑Label Disease‑Modifying Claims

The HEP2 prospective cohort shows that most patients with focal treatment‑resistant epilepsy experienced substantial seizure reductions over 18–36 months; ASM additions produced modest gains but rarely achieved freedom, and device-treated p

Dec 7, 2025

Cardiology

Early Childhood High Blood Pressure Predicts Premature Cardiovascular Mortality: Insights from a 50-Year Longitudinal US Cohort

Elevated blood pressure at age 7 significantly increases the risk of premature cardiovascular mortality by mid-adulthood, underscoring the need for early-life blood pressure monitoring and intervention.

Sep 7, 2025