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Longitudinal Weight Changes in MASLD: Impact on Liver Outcomes and Disease Progression
Diabetes & EndocrinologyobesityMASLD

Longitudinal Weight Changes in MASLD: Impact on Liver Outcomes and Disease Progression

By MedXY|Aug 19, 2026

This study reveals that weight gain exceeding 5% in MASLD patients increases liver-related event risks and liver stiffness, whereas weight loss improves liver stiffness and may reduce adverse outcomes, especially with obesity reversal.

Comparative Effectiveness of Shear Wave Elastography and VCTE in MASLD Risk Stratification: Insights from FIB-4-Based Two-Step Algorithms
Gastroenterologyrisk stratificationMASLD

Comparative Effectiveness of Shear Wave Elastography and VCTE in MASLD Risk Stratification: Insights from FIB-4-Based Two-Step Algorithms

By MedXY|Aug 15, 2026

Shear wave elastography (SWE) shows comparable accuracy to vibration-controlled transient elastography (VCTE) for stratifying liver-related event risk in MASLD patients using FIB-4-based two-step algorithms.

Cardiovascular-Kidney-Metabolic Syndrome and Its Impact on Liver Fibrosis Progression and Liver-Related Events in MASLD
GastroenterologyMASLDcardiovascular-kidney-metabolic syndrome

Cardiovascular-Kidney-Metabolic Syndrome and Its Impact on Liver Fibrosis Progression and Liver-Related Events in MASLD

By MedXY|Aug 14, 2026

This article reviews evidence linking cardiovascular-kidney-metabolic syndrome stages to liver fibrosis severity, progression, and liver-related events in metabolic dysfunction-associated steatotic liver disease (MASLD). Higher CKM stages i

New Obesity Definitions Reclassify Many MASLD Patients but Do Not Improve Liver Risk Prediction
GastroenterologyMASLDliver-related events

New Obesity Definitions Reclassify Many MASLD Patients but Do Not Improve Liver Risk Prediction

By MedXY|Jul 28, 2026

New obesity definitions reclassify many MASLD patients as obese but do not improve prediction of liver-related events over BMI alone, according to a multinational cohort study.

Comparative Risks of MASLD and MetALD: Insights from a Comprehensive Meta-Analysis on Hepatic and Extrahepatic Outcomes
Gastroenterologyhepatocellular carcinomaliver-related events

Comparative Risks of MASLD and MetALD: Insights from a Comprehensive Meta-Analysis on Hepatic and Extrahepatic Outcomes

By MedXY|Oct 19, 2025

This meta-analysis reveals that MetALD confers higher risks of liver-related events, hepatocellular carcinoma, and extrahepatic cancers compared to MASLD, while mortality and cardiovascular risks are similar, emphasizing tailored clinical a

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