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This study reveals that female stroke patients are less frequently screened for large vessel occlusion (LVO) yet have a higher LVO prevalence and comparable thrombectomy use to males, with better long-term outcomes post-thrombectomy.
In a randomized trial of large-vessel-occlusion stroke, standard-dose tenecteplase improved early reperfusion before thrombectomy compared with low-dose alteplase, with similar safety and functional outcomes.
In patients with large-vessel-occlusion stroke undergoing thrombectomy, standard-dose tenecteplase achieved more early reperfusion than low-dose alteplase, with similar safety and functional outcomes.
This review synthesizes recent evidence comparing ‘mothership’ and ‘drip-and-ship’ strategies in acute ischemic stroke, highlighting functional benefits of direct transport and the critical 43-minute delay threshold.
A large multinational RES-Q registry analysis suggests that the benefit of bridging thrombolysis before thrombectomy is greatest when treatment starts very early, with attenuation after 150 minutes.
A multicenter retrospective cohort found that IV thrombolysis started beyond 4.5 hours and before interhospital transfer for EVT was associated with higher rates of spontaneous recanalization during transfer and better 3‑month functional ou
A recent randomized clinical trial demonstrates that 0° head-of-bed positioning prior to thrombectomy in patients with large vessel occlusion stroke preserves neurological stability and reduces mortality compared to the conventional 30° ele
The SUMMIT MAX randomized trial demonstrates that the super large bore HiPoint reperfusion system is noninferior to the Vecta system in reperfusion success and safety for acute ischemic stroke due to large vessel occlusion.
