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SLA-DR–Deleted Donor Pigs Show Durable Kidney Xenograft Function and a Favorable Safety Profile in Rhesus Monkeys
General Surgerykidney transplantrhesus monkey

SLA-DR–Deleted Donor Pigs Show Durable Kidney Xenograft Function and a Favorable Safety Profile in Rhesus Monkeys

By MedXY|Jun 6, 2026

CRISPR-engineered GGTA1/B4GALNT2/SLA-DR knockout pigs remained healthy, screened negative for 55 zoonotic pathogens, and supported long-term renal xenograft function in rhesus monkeys when preformed anti-SLA antibodies were absent.

IXA Position Paper: Practical Roadmap for First-in-Human Porcine Kidney Xenotransplantation
Nephrologykidney transplantxenotransplantation
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IXA Position Paper: Practical Roadmap for First-in-Human Porcine Kidney Xenotransplantation

By MedXY|Oct 28, 2025

The International Xenotransplantation Association (IXA) 2025 position paper offers evidence-based recommendations for initial clinical trials of genetically engineered porcine kidney transplants for end-stage renal disease, focusing on dono

Mitigating Risks of Donor-Derived Epstein-Barr Virus Infection in Pediatric Kidney Transplantation: Advances and Challenges
Infectious DiseasesEBVInfection Risk

Mitigating Risks of Donor-Derived Epstein-Barr Virus Infection in Pediatric Kidney Transplantation: Advances and Challenges

By MedXY|Oct 27, 2025

This article reviews recent studies on EBV transmission in pediatric kidney transplants, highlighting risk factors, monitoring strategies, and implications for reducing posttransplant lymphoproliferative disorder (PTLD).

Enhancing Cardiovascular Health in Kidney Transplant Recipients: Updated Evidence on Physical Activity Interventions
Cardiologycardiovascular diseaseexercise therapy

Enhancing Cardiovascular Health in Kidney Transplant Recipients: Updated Evidence on Physical Activity Interventions

By MedXY|Oct 12, 2025

An updated meta-analysis of 23 RCTs reveals that physical activity improves cardiorespiratory fitness and HDL cholesterol in adult kidney transplant recipients, suggesting important cardiovascular benefits despite current study limitations.

Kidney-transplant recipients benefit from COVID-19 vaccination
Infectious DiseasesCOVID-19kidney transplant

Kidney-transplant recipients benefit from COVID-19 vaccination

By MedXY|Oct 4, 2025

Kidney-transplant recipients on long-term kidney replacement therapy demonstrate significant reductions in COVID-19-related hospitalizations and mortality following three or more vaccine doses, supporting booster vaccinations in this vulner

Understanding Pregnancy Risks in Kidney Transplant Recipients Using ART
newsARTkidney transplant

Understanding Pregnancy Risks in Kidney Transplant Recipients Using ART

By MedXY|Sep 30, 2025

Exploring increased pregnancy risks associated with assisted reproductive technology in kidney transplant recipients and its implications for clinical care.

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