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A comprehensive evidence-based synthesis of the REMAP-CAP trial and major international RCTs, demonstrating that ivermectin fails to improve clinical outcomes, survival, or organ support requirements in hospitalized and non-hospitalized COV
A large-scale multicentre clinical trial reveals that 5% permethrin cream is significantly more effective than oral ivermectin for treating scabies in households, providing crucial evidence for public health and clinical practice.
Large-scale trials in Kenya and Mozambique demonstrate that ivermectin mass drug administration significantly reduces malaria incidence by 26% and lowers community scabies prevalence, providing both direct protection and indirect herd-like
Two randomized trials from Pemba Island show orodispersible ivermectin–albendazole yields dose‑dependent high cure rates in preschool children, and moxidectin–albendazole is superior to albendazole alone in school‑aged children, both with a
Recent cluster-randomized trials in Kenya and Burkina Faso provide mixed but informative evidence on the efficacy and safety of mass ivermectin administration for malaria control, highlighting both its potential and limitations.
