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Islet Autoimmunity

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Diabetes & Endocrinology

Evaluating Beta Cell Function in Preclinical Type 1 Diabetes Using CGM-Derived Disposition Index

A novel CGM-derived disposition index reliably estimates beta cell function in individuals with islet autoimmunity without insulin therapy, predicting glycemic deterioration one year later.

Oct 14, 2026Sign in to read
Diabetes & Endocrinology

Unraveling Maternal Protection Against Type 1 Diabetes: Genetic Risk and Intrauterine Influences

This study reveals that the reduced risk of type 1 diabetes in children born to mothers with the condition is not due to genetic differences but possibly to protective intrauterine exposures during early childhood.

Oct 7, 2026
Diabetes & Endocrinology

Rising Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes: Insights From Longitudinal Cohorts

A study reveals a significant secular increase in islet autoimmunity incidence among Colorado children from 1993 to 2010, particularly in those with moderate-risk HLA genotypes, highlighting evolving risk profiles beyond known environmental

Sep 11, 2026
Diabetes & Endocrinology

Fecal Short-Chain Fatty Acids in Mother-Infant Dyads: No Direct Link to Islet Autoimmunity Development

A longitudinal study shows no association between fecal short-chain fatty acid levels during pregnancy and early childhood with the progression to islet autoimmunity in children at risk for type 1 diabetes.

Aug 24, 2026Sign in to read
Clinical Updates

Lifestyle Determinants and Metabolic Compensation in Pregnancies Complicated by Type 1 Diabetes: A Synthesis of the ENDIA Study and Recent Evidence

This review analyzes the lifestyle patterns of pregnant women with type 1 diabetes, synthesizing findings from the ENDIA study with recent evidence on nutritional adequacy, islet autoimmunity, and the molecular mechanisms of metabolic compe

Mar 12, 2026

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