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Insulin Therapy

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Critical Care

Timing Matters: Early Insulin Therapy Reduces Mortality in ICU Patients with Moderate Hyperglycemia

Early initiation of insulin within two hours for moderate hyperglycemia in ICU patients significantly lowers 30-day mortality compared to delayed or no insulin therapy. This target trial emulation highlights the potential clinical benefit o

Aug 17, 2026
Diabetes & Endocrinology

Beyond the Needle: GRADE Trial Debunks Myths on Insulin Distress and Confirms Adherence as the Glycemic Key

A comprehensive analysis of the GRADE trial substudies reveals that adding basal insulin does not increase emotional distress in early T2DM and highlights the critical, predictive link between medication adherence and long-term glycemic suc

Feb 2, 2026

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