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A comprehensive case-control study published in The Lancet Regional Health – Americas highlights how Intensity-Modulated Proton Therapy (IMPT) significantly reduces toxicities and improves quality of life for nasopharyngeal carcinoma
A case-control study comparing IMPT and IMRT for nasopharyngeal carcinoma shows that IMPT significantly reduces grade 2+ acute toxicities without compromising long-term survival or local-regional control, suggesting a superior therapeutic i
In a large single‑institution cohort of oropharyngeal squamous cell carcinoma, proton therapy was associated with a higher 3‑year rate of osteoradionecrosis than IMRT (6.4% vs 2.7%), though severe ORN remained uncommon.
A large single-center cohort (n=7,622) shows 12.6% of head and neck cancer patients develop severe (≥RTOG grade 3) radiation-related late toxicities; modifiable factors and specialized multidisciplinary late-effects care may reduce risk and
A multicenter propensity-matched cohort comparing adjuvant proton beam radiotherapy (PBRT) with intensity-modulated radiotherapy (IMRT) for olfactory neuroblastoma found no definitive differences in local control, recurrence-free survival,
A multi-institutional propensity-matched cohort found no definitive differences in oncologic outcomes or grade ≥2 radiotherapy toxicities between adjuvant proton beam radiotherapy and IMRT for olfactory neuroblastoma, but estimates were imp