immunotherapy

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Perioperative Durvalumab Plus FLOT Improves Event-Free Survival in Resectable Gastric and Gastroesophageal Junction Cancer: Results from the MATTERHORN Trial

Adding perioperative durvalumab to standard FLOT chemotherapy significantly improves event-free survival and pathological response in resectable gastric and gastroesophageal junction adenocarcinoma without increasing severe adverse events.

Jul 31, 2025

Clinical Updates

Tarlatamab versus Chemotherapy in Relapsed Small-Cell Lung Cancer: Results from the Phase 3 DeLLphi-304 Trial

Tarlatamab significantly improves overall survival and reduces severe adverse events compared to chemotherapy in patients with small-cell lung cancer progressing after platinum-based therapy.

Jul 31, 2025

Allergy & Immunology

Cockroach Immunotherapy Modulates Key T-Cell Responses Regardless of Allergen Extract Abundance

A randomized trial finds that subcutaneous cockroach immunotherapy effectively downregulates dominant T-cell responses in pediatric asthma, independent of allergen abundance in the therapeutic extract.

Jul 30, 2025

Medical News

AI-Designed Proteins Revolutionize Personalized Cancer Treatment

AI-powered protein design offers a fast, personalized approach to cancer treatment, enhancing immune response and minimizing side effects.

Jul 25, 2025