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Adipocyte-Driven Immunometabolic Suppression in Pancreatic Cancer: The 12,13-DiHOME/PPARγ/TAN Axis

This review explores how tumour-infiltrating adipocytes release 12,13-DiHOME to trigger neutrophil ferroptosis and CXCL2 production, ultimately subverting CD8+ T cell-mediated immunity in pancreatic ductal adenocarcinoma.

Jun 3, 2026
Diabetes & Endocrinology

Dietary Phytomix Dibifree Reshapes T2D Management by Modulating the Gut-Pancreas-Adipose-Immune Axis

A randomized trial demonstrates that Dibifree, a novel dietary phytomix, improves HbA1c and adiposity in T2D patients by enhancing GLP-1 activity and modulating immune responses.

Jan 11, 2026
Family Medicine & Nutrition

Unlocking the Body’s Natural ‘Fire Extinguisher’: How Vitamin B3 Enhances a Novel Anti-Inflammatory Molecule

A groundbreaking discovery reveals a natural anti-inflammatory molecule in the body, homocysitaconate, whose levels can be boosted by vitamin B3 supplementation, offering new hope for managing severe inflammatory diseases.

Aug 31, 2025

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