Immune tolerance

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Targeted Tolerance Induction in Pemphigus Vulgaris: A Synthesis of Phase I Clinical and Preclinical Evidence for TPM203 Nanoparticles

This review evaluates TPM203, a novel nanoparticle-based therapy for Pemphigus Vulgaris, detailing its safety profile, rapid pharmacokinetics, and ability to modulate regulatory T-cell and memory B-cell populations to induce immune toleranc

Mar 5, 2026Sign in to read

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Guardians Within: Unveiling the Nobel-Winning Discovery of Regulatory T Cells and Their Crucial Role in Immune Balance

The 2025 Nobel Prize honors the groundbreaking discovery of regulatory T cells (Tregs), key immune modulators that maintain tolerance and prevent autoimmunity, inspiring new therapies for autoimmune disease, transplantation, and cancer.

Oct 6, 2025

Allergy & Immunology

Guardians Within: The Nobel-Winning Discovery of Regulatory T Cells and Their Role in Immune Balance

The 2025 Nobel Prize in Physiology or Medicine honors groundbreaking work on regulatory T cells, revealing how the immune system avoids self-attack while combating threats, paving the way for novel therapies in autoimmune and transplant med

Oct 6, 2025