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Evaluating the ISOLD Score for Accurate Diagnosis of Vitreoretinal Lymphoma in Clinical Practice
Hematology-OncologyAqueous humorIL-10

Evaluating the ISOLD Score for Accurate Diagnosis of Vitreoretinal Lymphoma in Clinical Practice

By MedXY|Jul 9, 2026

This study validates the ISOLD score, a cytokine-based probabilistic tool, demonstrating high sensitivity and specificity for diagnosing vitreoretinal lymphoma from aqueous humor samples, outperforming standard IL-10/IL-6 ratios, with impli

IL‑10–Armored anti‑CD19 CAR T Cells for R/R B‑ALL: Promising Phase 1 Safety Signals and a New Strategy to Tame Inflammatory Toxicity
Hematology-OncologyB-ALLCAR-T

IL‑10–Armored anti‑CD19 CAR T Cells for R/R B‑ALL: Promising Phase 1 Safety Signals and a New Strategy to Tame Inflammatory Toxicity

By MedXY|Nov 24, 2025

A phase 1, single‑arm study evaluated IL‑10–expressing anti‑CD19 CAR T cells in relapsed/refractory B‑ALL, reporting feasibility and encouraging safety signals suggesting attenuated inflammatory toxicity while preserving anti‑leukemic activ

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