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A multicentre RCT found that smartphone-based self-guided hypnotherapy did not meet non-inferiority to in-person therapy for IBS abdominal pain, though both hypnotherapy arms outperformed psychoeducation.
A genome-wide meta-analysis of 2.8 million individuals reveals genetic links between irritable bowel syndrome, brain-gut pathways, and cardiometabolic traits, highlighting novel therapeutic targets involving triglyceride metabolism.
The SOMA.GUT-RCT investigated a targeted psychological intervention for IBS and UC. While the primary 3-month endpoint showed no significant symptom reduction compared to standard care, exploratory data revealed significant psychological im
A new IBS diagnosis is associated with a transiently increased risk of ovarian cancer, especially within the first 6 months, emphasizing the need for heightened clinical vigilance.