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Predicting Hypothyroidism After Hemithyroidectomy: Development and Validation of a Clinical Nomogram for Personalized Risk Assessment
Diabetes & EndocrinologyHypothyroidismHemithyroidectomy

Predicting Hypothyroidism After Hemithyroidectomy: Development and Validation of a Clinical Nomogram for Personalized Risk Assessment

By MedXY|Sep 5, 2026

A validated nomogram predicts hypothyroidism risk within 12 months after hemithyroidectomy using clinical and pathological variables, aiding tailored patient counseling and postoperative monitoring.

Impact of Hypothyroidism on Short-Term and Long-Term Outcomes of Coronary Artery Bypass Graft Surgery
Clinical UpdatesCABG
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cardiovascular outcomes

Impact of Hypothyroidism on Short-Term and Long-Term Outcomes of Coronary Artery Bypass Graft Surgery

By MedXY|Jul 4, 2026

Hypothyroidism increases the incidence of CABG and is linked to higher risks of postoperative complications, heart failure, stroke, and major adverse cardiovascular events, highlighting the importance of preoperative thyroid function optimi

Levothyroxine Dosing and the Risk of Suboptimal Thyroid Control: Insights from a Large Real-World Longitudinal Study
Diabetes & Endocrinologydose-responseHypothyroidism

Levothyroxine Dosing and the Risk of Suboptimal Thyroid Control: Insights from a Large Real-World Longitudinal Study

By MedXY|Jul 3, 2026

This real-world study demonstrates a dose-dependent increase in suboptimal thyroid hormone control among adults treated with levothyroxine, emphasizing the need for enhanced TSH monitoring in patients on higher doses.

Phase 2 Study of XP-8121: Once-Weekly Subcutaneous Levothyroxine for Adult Hypothyroidism
Diabetes & EndocrinologyendocrinologyHypothyroidism

Phase 2 Study of XP-8121: Once-Weekly Subcutaneous Levothyroxine for Adult Hypothyroidism

By MedXY|Jun 5, 2026

A Phase 2 trial found that once-weekly subcutaneous levothyroxine (XP-8121) was generally well tolerated and suggested a dose conversion of about four times the daily oral dose for adults with hypothyroidism.

Long-Term Risk of Hypothyroidism After Thyroid Abnormalities Identified in Pregnancy
Diabetes & EndocrinologyPregnancy亜臨床性甲状腺機能低下症

Long-Term Risk of Hypothyroidism After Thyroid Abnormalities Identified in Pregnancy

By MedXY|Aug 18, 2026

Thyroid abnormalities found during pregnancy, especially when subclinical hypothyroidism and TPO antibodies coexist, can signal a much higher long-term risk of overt hypothyroidism, supporting ongoing thyroid follow-up after delivery.

Breaking the Fasting Mandate: Is It Time to Re-evaluate Levothyroxine Administration?
Diabetes & EndocrinologyendocrinologyHypothyroidism

Breaking the Fasting Mandate: Is It Time to Re-evaluate Levothyroxine Administration?

By MedXY|Mar 17, 2026

A randomized clinical trial demonstrates that a 15% dose increase allows levothyroxine to be taken with breakfast without compromising TSH stability, significantly improving patient preference and well-being.

Levothyroxine Monotherapy in Midlife Women: Long-Term SWAN Data Reassures on Cardiovascular Safety
Diabetes & Endocrinologycardiovascular diseaseHypothyroidism

Levothyroxine Monotherapy in Midlife Women: Long-Term SWAN Data Reassures on Cardiovascular Safety

By MedXY|Mar 12, 2026

A longitudinal analysis from the SWAN study indicates that women treated with levothyroxine for hypothyroidism do not face a higher risk of cardiovascular events compared to those without thyroid disease, providing clinical reassurance for

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