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Cardiology

Lorundrostat Lowers 24‑Hour Systolic Blood Pressure in Treatment‑Resistant Hypertension but Raises Hyperkalemia Concerns

A randomized, placebo‑controlled trial found lorundrostat reduced 24‑hour systolic BP by ~7–8 mm Hg versus placebo in patients with uncontrolled, treatment‑resistant hypertension; notable rates of marked hyperkalemia occurred only in active

Dec 6, 2025
Cardiology

DIALIZE-Outcomes Trial: Sodium Zirconium Cyclosilicate Effect on Cardiovascular Outcomes in Hemodialysis Patients with Hyperkalemia

The DIALIZE-Outcomes trial assessed sodium zirconium cyclosilicate (SZC) in controlling predialysis hyperkalemia among hemodialysis patients but found no reduction in arrhythmia-related cardiovascular events despite improved potassium contr

Sep 22, 2025

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