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HTD1801 Monotherapy Significantly Improves Glycemic Control and Cardiometabolic Health in Type 2 Diabetes: Results From a 56-Week Phase 3 Trial
Diabetes & EndocrinologyGlycemic Controltype 2 diabetes

HTD1801 Monotherapy Significantly Improves Glycemic Control and Cardiometabolic Health in Type 2 Diabetes: Results From a 56-Week Phase 3 Trial

By MedXY|Aug 25, 2026

A phase 3 trial demonstrated that HTD1801 monotherapy significantly reduces HbA1c and improves cardiometabolic and inflammatory markers in patients with inadequately controlled type 2 diabetes, with sustained effects and a favorable safety

HTD1801 Shows Promising Histologic Improvement in Metabolic Dysfunction-Associated Steatohepatitis: Insights from Preclinical and Phase 2 Clinical Studies
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HTD1801 Shows Promising Histologic Improvement in Metabolic Dysfunction-Associated Steatohepatitis: Insights from Preclinical and Phase 2 Clinical Studies

By MedXY|Oct 4, 2025

HTD1801 (berberine ursodeoxycholate) significantly improves liver histology and reduces fibrosis in metabolic dysfunction-associated steatohepatitis (MASH) as demonstrated by preclinical models and a Phase 2 trial.

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