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HSP72-PRDX6 Control of PINK1 Ubiquitination Emerges as a New Mitophagy Axis in MASLD
GastroenterologyHSP72MASLD

HSP72-PRDX6 Control of PINK1 Ubiquitination Emerges as a New Mitophagy Axis in MASLD

By MedXY|May 1, 2026

A new Hepatology study identifies an HSP72–PRDX6 pathway that restores PINK1/Parkin mitophagy, reduces hepatic steatosis, and worsens MASLD when disrupted in mice and hepatocytes.

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