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Hematology-Oncology

Impact of Clonal Hematopoiesis and Pre-treatment Neutropenia on CAR-T Cell Therapy Outcomes in Hematological Malignancies

This study evaluates how clonal hematopoiesis of indeterminate potential (CHIP) and pre-treatment neutropenia affect clinical outcomes and toxicities in patients undergoing CAR-T therapy for hematologic cancers, revealing nuanced risks for

Oct 9, 2026Sign in to read
Hematology-Oncology

Influence of Clonal Hematopoiesis and Neutropenia on CAR-T Therapy Outcomes in Hematologic Malignancies

CHIP and pre-treatment neutropenia do not significantly affect survival or main toxicities in CAR-T therapy for hematologic cancers but may predict specific inflammatory toxicities, indicating distinct risk profiles for patient management.

Oct 8, 2026

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