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Hematology-Oncology

Estimating the National Impact of Severe Hemolytic Disease of the Fetus and Newborn in the United States

A large-scale analysis estimates the U.S. national burden of severe hemolytic disease of the fetus and newborn (HDFN) caused by anti-D, anti-K, and anti-c alloantibodies, revealing that severe HDFN is rare despite common alloimmunization.

Nov 4, 2026
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Maternal Nipocalimab Therapy for Severe HDFN: Evidence of Neonatal Safety and Immunological Recovery

The UNITY study demonstrates that antenatal nipocalimab treatment for severe HDFN effectively reduces fetal risk while resulting in only transient neonatal hypogammaglobulinemia. Findings confirm low fetal drug exposure and robust long-term

Jan 31, 2026

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