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Surgical randomized trials in gynecologic oncology revolutionize treatment approaches, but sustainability beyond publication requires structured implementation, credentialing, and vigilant post-trial surveillance to maintain safety, equity,
This study highlights the prevalence, clinical features, and management challenges of immune-related thyroid and diabetes toxicities in gynecologic cancer patients treated with immunotherapy, emphasizing the need for proactive endocrine mon
This article reviews a study identifying key factors contributing to delays in diagnosing vulvar squamous cell carcinoma, emphasizing provider and system-level influences and the need for timely biopsy and specialist referrals.
This review contrasts early- and late-phase gynecologic oncology trials, underscoring disparities in trial completion, publication, and racial/ethnic minority enrollment, highlighting the need to improve inclusivity and reporting.
A pilot program using former gynecologic oncology trial participants as patient ambassadors improved confidence and perceptions about clinical trials among trial-naïve patients, highlighting a feasible peer-education approach.
A study benchmarking large language models in gynecologic oncology demonstrates that guideline-anchored retrieval-augmented generation (RAG) configurations outperform baseline and literature-only AI systems in clinical decision support, hig
This study identifies key patient-level factors associated with failure to rescue after major gynecologic oncology surgery, emphasizing complication severity and physiological reserve over procedure complexity.
A Danish multicenter study found that adding HE4 to the IOTA ADNEX model offered only limited, threshold-dependent benefit for assessing adnexal masses, with no meaningful improvement in non-tertiary centers.
A culturally tailored educational intervention significantly improved clinical trial knowledge and self-efficacy among African American and Hispanic women, highlighting the potential of community partnerships to address disparities in gynec
In a prospective cohort of 172 vulvar surgery patients, prophylactic antibiotics were not associated with fewer postoperative infections or complications, supporting the need for a randomized trial.
A prospective study evaluating at-home stool collection for gut microbiome research in gynecologic oncology demonstrates implementation feasibility with 61% patient enrollment. Provider engagement emerged as the strongest predictor of parti
This evidence-based review examines the significant disparity in NIH funding for cancer survivorship, revealing that gynecologic cancer research receives nearly five times less funding per survivor than breast cancer research.
This study of 1,351 high-risk women demonstrates that while risk-reducing salpingo-oophorectomy (RRSO) is effective, the presence of serous tubal intraepithelial carcinoma (STIC) at the time of surgery significantly increases the 5-year ris
The GOG 3026 phase II trial demonstrates that the combination of ribociclib and letrozole provides significant clinical benefit and durable responses in patients with recurrent low-grade serous carcinoma, representing a major step forward f
