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The ISOREA survey highlights significant geo-economic disparities in ICU resources and organization worldwide, revealing critical gaps in critical care capabilities particularly in low-income settings, with implications for global health eq
A global study identifies key hospital-level modifiable resources that reduce 90-day mortality after pancreas surgery and introduces a composite Hospital Resource Index to guide improvements beyond surgical volume centralization.
This study analyzes global trends comparing ischemic stroke burdens linked to diabetes and atrial fibrillation, revealing a rising impact of diabetes-related stroke and highlighting the need for targeted interventions.
This review explores the Global Lymphoma Registry Alliance’s roadmap for leveraging multinational real-world data collaborations to address lymphoma’s heterogeneity, optimize treatment strategies, and improve patient outcomes worldwide thro
New region- and sex-specific axial length centile charts provide vital reference values for myopia monitoring and management in children, highlighting regional differences and supporting targeted interventions against rising myopia rates.
In a large international prospective cohort of hospitalized patients with cirrhosis, chronic kidney disease was common, clustered with metabolic risk, and strongly associated with acute kidney injury, more decompensation, and higher in-hosp
The PURE study reveals significant global disparities in heart failure incidence and mortality, with hypertension as the leading modifiable risk factor, highlighting the need for targeted prevention and treatment strategies.
This review analyzes global radiation doses in CAD diagnostic imaging based on the INCAPS 4 study. It highlights significant disparities across modalities and regions, revealing that patients in low-income countries and those undergoing CCT
A randomized, double-blind trial in Kenya and Uganda reveals that a 500 IU fractional dose of yellow fever vaccine is not non-inferior to the standard dose in infants, suggesting that lower dose requirements in adults are not generalizable
A landmark pragmatic randomized controlled trial in Vietnam reveals that proactive Quitline referrals are as effective as nurse-led counseling and nicotine replacement therapy for smoking cessation among people living with HIV, offering a s
A landmark longitudinal study reveals that 10.6 million children experience serious health-related suffering annually, with a critical shift toward survivors requiring long-term palliative support rather than end-of-life care, predominantly
A large-scale multicohort study reveals that adult obesity significantly increases the risk of hospitalization and death across nearly 1,000 infectious diseases, accounting for approximately one in ten infection-related deaths globally.
A 30-year analysis reveals that 10.6 million children experience serious health-related suffering annually, with a massive shift toward chronic, non-decedent care needs in low- and middle-income countries.
A randomized clinical trial in Jamaica demonstrates that a hybrid model of in-person and remote parenting support delivered via primary care significantly improves child developmental outcomes and parenting behaviors, offering a scalable so
By 2050, global gastrointestinal cancer incidence is projected to surge by 85%, reaching 9.06 million cases annually. While gastric cancer rates are declining, colorectal and pancreatic cancers are rising sharply, particularly in low and me
From 2010 to 2019, NCD mortality declined in 80% of countries worldwide, driven primarily by reductions in circulatory diseases, with notable regional and cause-specific heterogeneity and slower progress than the previous decade.
A comprehensive study spanning 47 countries reveals changing suicide mortality rates among adults aged 65+, highlighting method-specific risks and projecting future trends amid global population ageing.
A comprehensive analysis reveals ongoing challenges in diabetes diagnosis, treatment, and glycaemic control worldwide, highlighting the urgent need for enhanced care strategies, especially in low- and middle-income regions.
Discover how a parasitic worm quietly invades the human body, evading pain and immune detection, causing millions of infections and thousands of deaths annually, with its spread now threatening new regions amid climate change and travel.
Analysis of WHO data reveals declining global pulmonary embolism mortality overall, with marked differences by region and income, highlighting urgent needs in lower-middle-income countries.
