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This study identifies serum and gene expression signatures predicting successful canakinumab tapering in systemic juvenile idiopathic arthritis, offering precision medicine strategies to reduce flares.
A longitudinal blood gene-expression study in children found an early neutrophil-driven immune pattern at age 1, followed by a persistent eosinophilic signature from 4.5 to 10.5 years in those who later developed asthma.
This study used immune-cell gene expression and genetic analyses to identify causal genes and immune pathways linked to type 2 diabetes and its complications, highlighting diabetic neuropathy as a distinct cluster and prioritising ten promi
This review explores the transcriptomic distinctions between vocal fold polyps and Reinke’s edema, focusing on the upregulation of COL1A1, FN1, and MMP-9 in polyps as key diagnostic and mechanistic markers.
Research indicates that the sensation of hunger triggered by calorie restriction can influence gene expression, helping to delay aging and extend lifespan by up to 35%.
