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High-Impact Physical Activity and Joint Replacement Risk in Hip and Knee Osteoarthritis: A Large-Scale Longitudinal Mediation Study

High-impact physical activity in patients with hip osteoarthritis is associated with a reduced 12-month risk of total hip replacement, without increasing knee replacement risk in knee OA patients. Functional capacity partly mediates this be

Oct 21, 2026
Diabetes & Endocrinology

Nutritional Intervention in Chronic Heart Failure: Enhancing Functional Capacity and Nutritional Status without Major Clinical Outcome Impact

A prespecified subanalysis of the PACMAN-HF trial demonstrates that individualized nutritional interventions in chronic heart failure patients at risk of malnutrition improve nutritional status and functional capacity but do not significant

Sep 16, 2025

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  1. 01Intimate Health

    Five Benefits for Women Continuing Sexual Activity After Menopause

  2. 02Intimate Health

    Why Some Women Have a Strong Sex Drive—And Why Men Shouldn't Worry About It

  3. 03Nursing & care

    How often should a couple have sex?

  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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