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Nephrology

Selective TRPC6 Inhibition Emerges as a Novel Therapeutic Paradigm for Focal Segmental Glomerulosclerosis

A Phase 2 trial of BI 764198, a selective TRPC6 inhibitor, demonstrates significant proteinuria reduction in patients with focal segmental glomerulosclerosis. This study provides the first clinical evidence for podocyte-targeted therapy, ma

Feb 16, 2026
Clinical Updates

Enhancing Prognosis in FSGS and MCD through Computational Tubular Feature Analysis

Computational quantification of tubular structures in kidney biopsies improves prognostic accuracy in focal segmental glomerulosclerosis and minimal change disease by revealing spatial relationships with interstitial fibrosis.

Aug 12, 2025Sign in to read

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