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Ketamine vs. Etomidate: Does Your Choice of Induction Agent Influence Mortality in the Critically Ill?

By MedXY|Dec 18, 2025

This article explores recent evidence comparing ketamine and etomidate for rapid sequence intubation. While new cohort data suggests a mortality benefit for ketamine, meta-analyses of randomized trials show clinical equipoise, highlighting

Anesthesiologycritical careEtomidate

Ketamine or Etomidate for Tracheal Intubation? Unpacking the RSI Trial Findings on Mortality and Hemodynamics

By MedXY|Dec 18, 2025

The large-scale RSI randomized trial found no significant difference in 28-day mortality between ketamine and etomidate for intubating critically ill adults, though ketamine was associated with a higher risk of cardiovascular collapse.