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Gastroenterology

More is Not Always Better: The GOULASH Trial Challenges High-Energy Early Nutrition in Acute Pancreatitis

The multicentre GOULASH trial reveals that high-energy nutrition in the early phase of acute pancreatitis does not improve outcomes and may increase risks of organ failure and pain relapse compared to a gradual caloric increase, leading to

Mar 7, 2026Sign in to read
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Supplemental Donor Human Milk Did Not Speed Full Enteral Feeding in Moderate–Late Preterm Infants: Results From a Multisite Randomized Trial

In a blinded multisite RCT of 201 moderate–late preterm infants, short-term supplementation with pasteurized donor human milk versus term formula did not shorten time to full enteral feeds; donor milk was associated with slower regain of bi

Dec 14, 2025
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Full Milk Feeds From Day 1 in Late Preterm Infants: Large RCT Shows No Shorter Hospital Stay and No Signal for Increased NEC or Hypoglycaemia

The FEED1 trial randomized 2088 infants born at 30+0 to 32+6 weeks to full enteral feeds from day 1 versus gradual feeding with IV support. Full feeds did not shorten hospital stay and showed no increase in necrotising enterocolitis or clin

Dec 1, 2025

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