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Researchers identify HEG1 as a critical flow-sensitive endothelial protein that regulates blood pressure through CUL3-mediated degradation of PHACTR1, linking reduced shear stress in hypertension to impaired NO production and vascular dysfu
This study identifies TCDCA as a key metabolite that restores endothelial function in obesity. By activating the endothelial FXR-PHB1-ATF4 pathway, TCDCA enhances serine metabolism, offering a promising therapeutic strategy to mitigate card
A cross-sectional study found lower brachial flow‑mediated dilation in chronic marijuana smokers and THC‑edible users versus nonusers; smoked cannabis sera also impaired VEGF‑stimulated NO production in endothelial cells, suggesting distinc
New animal research links oral microplastic exposure to dramatic increases in arterial plaque—especially in males—by injuring endothelial cells and provoking inflammation and oxidative stress.
A controlled study from the University of New South Wales shows a single high‑fat meal (130 g fat) produces marked postprandial hypertriglyceridaemia and measurable declines in systemic endothelial function and dynamic cerebral autoregulati
