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Emergency Medicine

One in Six Older Adults Presenting to the Emergency Department Had Delirium, With Higher Admission and 30-Day Readmission Risk

A large multi-site cohort found delirium in 16% of older ED patients, including many discharged home, and linked it to higher admission and 30-day readmission, underscoring the need for standardized screening and supportive care.

Jun 4, 2026
Emergency Medicine

Clinical Care Guideline Implementation of Nebulized Tranexamic Acid in Post-Tonsillectomy Hemorrhage

A clinical care guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage was rapidly adopted in the Emergency Department and was associated with fewer returns to the operating room.

Jun 1, 2026
Emergency Medicine

A Clinical Care Guideline for Nebulized Tranexamic Acid Was Associated With Fewer Operating Room Returns After Post-Tonsillectomy Hemorrhage

A structured emergency department guideline for nebulized tranexamic acid in post-tonsillectomy hemorrhage achieved rapid protocol uptake and was associated with a marked reduction in operative hemorrhage control.

Jun 1, 2026
Emergency Medicine

A Standardized Emergency Department Guideline for Nebulized Tranexamic Acid Was Linked to Fewer Operating Room Returns After Post-Tonsillectomy Hemorrhage

A hospital clinical care guideline enabled rapid uptake of nebulized tranexamic acid for eligible post-tonsillectomy hemorrhage and was associated with a marked reduction in operative control of bleeding.

Jun 1, 2026Sign in to read
Emergency Medicine

A Post-Tonsillectomy Hemorrhage Guideline With Nebulized Tranexamic Acid Was Linked to Fewer Returns to the Operating Room

A quality-improvement guideline standardizing nebulized tranexamic acid for post-tonsillectomy hemorrhage achieved high protocol adherence and was associated with a marked reduction in operative hemorrhage control.

Jun 1, 2026
Emergency Medicine

Digital Shared Decision Support Increased STI Testing for Adolescents and Young Adults in the Emergency Department

In a randomized controlled trial, the STIckER smartphone-based decision aid increased gonorrhea/chlamydia and pharyngeal STI testing in emergency department patients aged 14 to 24 years, while improving decisional clarity, satisfaction, and

May 30, 2026Sign in to read
Emergency Medicine

An Emergency Department Nudge-Based Strategy to Screen and Treat Patients With Alcohol Misuse

A multicomponent emergency department workflow using screening, electronic prompts, and discharge decision support significantly increased naltrexone prescribing for patients with alcohol-related diagnoses.

May 27, 2026
Emergency Medicine

Intravenous Magnesium Sulfate for Acute Nontraumatic Headache in the Emergency Department

Intravenous magnesium sulfate added to paracetamol increased early headache-treatment success in the emergency department, but the pain relief was modest and below usual clinical importance thresholds. It also reduced rescue analgesia needs

May 22, 2026
Cardiology

A New hs-cTnT Generation 6 Assay Matches Generation 5 for Myocardial Infarction Diagnosis While Labeling Fewer Patients as Myocardially Injured

In suspected myocardial infarction, hs-cTnT-gen6 showed diagnostic accuracy comparable to gen5, produced fewer myocardial injury classifications, and supported highly sensitive ESC 0/1-hour and 0/2-hour rule-out and rule-in pathways using a

May 9, 2026
Superintelligence

Ambient AI Scribes Reduced Emergency Department Documentation Time, but Early Adoption Was Limited and Highly Concentrated

In a real-world academic emergency department, ambient AI scribe use was uncommon and concentrated among a small group of physicians, but when used it was associated with shorter documentation and total EHR time.

May 5, 2026
Cardiology

LEGEND Trial: A Game-Changer in Rapid Rule-Out of Acute Myocardial Infarction in the ED

The LEGEND trial demonstrates that a high-sensitivity troponin-based rule-out strategy significantly reduces hospital length of stay and cardiac testing while safely excluding acute myocardial infarction in emergency department patients.

Apr 24, 2026
Cardiology

ED-Delivered Education Plus mHealth Lowers Systolic BP — TOUCHED Trial Shows a Modest but Meaningful 4.9 mm Hg Reduction at 6 Months

The TOUCHED randomized trial found that an ED-initiated education plus mHealth and pharmacist/APRN consultation reduced systolic blood pressure by 4.9 mm Hg at 6 months versus usual care in patients discharged with elevated BP.

Dec 5, 2025
Clinical Updates

Optimizing Gonorrhea and Chlamydia Screening for Adolescents in Emergency Departments: Evidence from Targeted and Universal Strategies

Comparative effectiveness evidence from multicenter pediatric emergency departments demonstrates that targeted and universally offered gonorrhea and chlamydia screening increase detection rates versus usual care, highlighting the need for i

Oct 27, 2025
Emergency Medicine

Optimizing Hepatitis C Screening in Emergency Departments: Insights from the DETECT Hep C Randomized Clinical Trial

The DETECT Hep C trial demonstrates nontargeted HCV screening in emergency departments identifies more new infections than risk-based approaches, though linkage to care remains suboptimal, underscoring the need for innovative treatment mode

Sep 11, 2025
Clinical Updates

Intensive Nurse Home Visiting and Early Childhood Outcomes: A Randomized Clinical Trial

A randomized trial assessing the impact of Nurse-Family Partnership home visits on child health and utilization over two years found no significant reduction in adverse outcomes but some decrease in emergency department use.

Aug 4, 2025
Clinical Updates

Opioid Prescribing Down, Imaging Steady: Patterns in US ED Management of Low Back Pain, 2016–2022

A large national study shows opioid prescribing for ED low back pain fell sharply from 2016 to 2022, while radiograph use remained high and unchanged.

Jul 30, 2025
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