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In this multicentre cohort of 207 hospitalized adults with DRESS, 17% required ICU care. Hospital-acquired DRESS and greater clinical severity independently predicted ICU admission, while ICU mortality reached 20%.
A large FAERS analysis links immune checkpoint inhibitors (ICIs) to markedly increased SJS/TEN risk, demonstrates additive synergy with high‑risk small molecules, and shows delayed latency particularly with anti–PD‑1 agents — supporting a t
Nearly half of adolescents and adults who developed penicillin-associated rashes during EBV infection exhibit persistent hypersensitivity, challenging the notion of transient viral exanthem-related allergies.
