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distant disease-free survival

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Neurology

Adjuvant Radiotherapy Reduces Recurrence After Complete Resection of WHO Grade 2 Atypical Meningioma: Insights from the ROAM/EORTC-1308 Phase 3 Trial

The ROAM/EORTC-1308 trial demonstrates that adjuvant radiotherapy after complete surgical resection of atypical meningioma significantly improves 5-year disease-free survival, reducing recurrence risk with manageable adverse effects.

Oct 16, 2026
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Distant Disease‑Free Survival Is a Reliable Surrogate for Overall Survival in Most Neoadjuvant Early Breast Cancer Trials — but Not All Subtypes

A pooled individual‑patient analysis of 11 neoadjuvant RCTs (12,247 patients) finds distant disease‑free survival (DDFS) strongly predicts overall survival (OS) trial‑level effects overall (R2trial=0.91), with weakened surrogacy in hormone‑

Nov 30, 2025Sign in to read

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