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Ten Years of Ocrelizumab in Relapsing Multiple Sclerosis: Insights from the OPERA I and II Randomized Clinical Trials and Related Evidence

Continuous ocrelizumab treatment over 10 years in relapsing MS significantly delays disability progression, reduces relapse rates, and maintains a favorable safety profile, underscoring the clinical benefit of early high-efficacy therapy.

Oct 10, 2026Sign in to read
Neurology

Paramagnetic Rim Lesions as Predictors of Progression in Multiple Sclerosis: Insights from a 5-Year Longitudinal Study

Paramagnetic rim lesions detected via MRI are associated with increased risk of disability progression independent of relapse activity and accelerated brain atrophy in multiple sclerosis, highlighting their role as prognostic biomarkers for

Aug 22, 2026
Allergy & Immunology

Menopause and Multiple Sclerosis: Evaluating the Impact on Disability Progression

A comprehensive analysis reveals that menopause does not significantly alter the risk of disability progression in women with relapse-onset multiple sclerosis, underscoring the complexity of reproductive aging’s role in disease trajec

Sep 29, 2025
Allergy & Immunology

Pregnancy and Disease Outcomes in Women with Moderate to Severe Multiple Sclerosis Disability

This study evaluates how pregnancy affects relapse rates and long-term disability in women with moderate to severe multiple sclerosis (MS), showing pregnancy reduces relapse during gestation without worsening long-term disability progressio

Sep 24, 2025

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    Five Benefits for Women Continuing Sexual Activity After Menopause

  2. 02Intimate Health

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  3. 03Nursing & care

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  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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