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Evaluating Androgen Receptor Inhibition Combined with Hormonal Therapies in Recurrent Adult-Type Ovarian Granulosa Cell Tumor: Insights from a Phase II Study
newsdarolutamideandrogen receptor inhibition

Evaluating Androgen Receptor Inhibition Combined with Hormonal Therapies in Recurrent Adult-Type Ovarian Granulosa Cell Tumor: Insights from a Phase II Study

By MedXY|Aug 18, 2026

A Phase II trial assessed the combination of darolutamide, leuprolide acetate, and exemestane in recurrent adult-type ovarian granulosa cell tumor, showing limited objective response but clinically meaningful progression-free survival witho

Optimizing Therapy for Older Patients with Metastatic Hormone-Sensitive Prostate Cancer: Insights from a Network Meta-Analysis of Doublet versus Triplet Regimens
newsdarolutamidemetastatic hormone-sensitive prostate cancer

Optimizing Therapy for Older Patients with Metastatic Hormone-Sensitive Prostate Cancer: Insights from a Network Meta-Analysis of Doublet versus Triplet Regimens

By MedXY|Oct 30, 2025

This network meta-analysis reveals that triplet therapy with darolutamide, ADT, and docetaxel offers the greatest overall survival benefit for older patients with metastatic hormone-sensitive prostate cancer, highlighting the need to balanc

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