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Family Medicine & Nutrition

The Double-Edged Sword of Curcumin: How Excessive Turmeric Supplements Can Harm Your Liver

While turmeric’s liver-regenerating benefits are celebrated, excessive intake of its active compound, curcumin, may cause serious liver damage. Understanding safe dosages and risks is critical for health.

Sep 21, 2025
Diabetes & Endocrinology

Enhanced Therapeutic Benefits of Combined Metformin and Curcumin in Women with Polycystic Ovary Syndrome: Results from a Factorial Clinical Trial

A 12-week randomized trial demonstrates that combining metformin and nanocurcumin significantly improves lipid metabolism, glucose regulation, hormonal balance, and body metrics in women with PCOS, surpassing effects seen with either agent

Sep 16, 2025
Cardiology

Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence

Current evidence supports curcumin supplementation for reducing cardiovascular risk factors and preventing type 2 diabetes progression, with emerging potential in cognitive decline and aging-related degenerative diseases.

Aug 18, 2025Sign in to read
Clinical Updates

Curcumin Mitigates Methotrexate-Induced Ovarian Damage: Insights into Antioxidant Protection via PARP-1 and P53 Modulation

Curcumin pretreatment reduces methotrexate-induced ovarian damage in rats by regulating oxidative stress and apoptosis pathways, highlighting a potential strategy for fertility preservation in chemotherapy.

Aug 6, 2025
Clinical Updates

Curcumin Shows Promise in Targeting Colorectal Cancer Stem-like Cells: Mechanistic Insights and Clinical Implications

Curcumin, derived from turmeric, targets colorectal cancer stem-like cells, inhibits tumor growth, and promotes differentiation, offering new opportunities for cancer prevention strategies.

Aug 6, 2025
Clinical Updates

Curcumin’s Impact on Serum Inflammatory Biomarkers in Knee Osteoarthritis: Evidence from a Systematic Review and Meta-Analysis

A systematic review and meta-analysis found that curcumin supplementation significantly reduces serum CRP and TNF-alpha in patients with knee osteoarthritis, but not other inflammatory biomarkers.

Aug 6, 2025

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