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Hematology-Oncology

Innovative Thrombin-Responsive AutoRegulated FVIII-Mimetic Antibodies for Safer Hemophilia A Therapy

A novel thrombin-cleavable FVIII-mimetic antibody enables dynamic, on-demand control of coagulation, reducing adverse thrombotic risk while maintaining efficacy in hemophilia A treatment.

Nov 1, 2026
Critical Care

International Validation of Sepsis Temperature-Trajectory Subphenotypes Reveals Immune and Coagulation Profiles with Implications for Immunoglobulin Therapy

This study validates temperature-trajectory sepsis subphenotypes in a large Chinese ICU cohort, linking immune and coagulation dysfunction with mortality and highlighting differential responses to immunoglobulin therapy, particularly benefi

Oct 1, 2026
Diabetes & Endocrinology

Persistent Plasma Protein Alterations After Long-Term Remission in Cushing’s Disease: Implications for Morbidity and Monitoring

This study reveals that despite long-term remission in Cushing’s disease, substantial plasma protein abnormalities persist, particularly in coagulation and complement systems, potentially contributing to ongoing health risks.

Sep 21, 2026
Cardiology

JCAD Protein: A Novel Predictor and Therapeutic Target for Residual Cardiovascular Risk in Acute Coronary Syndrome

JCAD, a junctional protein, independently predicts major adverse cardiovascular events (MACE) in acute coronary syndrome (ACS) patients with residual lipid and inflammatory risks, suggesting a key role in coagulation and fibrinolysis and a

Jul 30, 2026Sign in to read

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