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Clozapine Works Beyond Schizophrenia: Nationwide Evidence for Transdiagnostic Effectiveness and Safety
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Clozapine Works Beyond Schizophrenia: Nationwide Evidence for Transdiagnostic Effectiveness and Safety

By MedXY|Dec 1, 2025

Large Finnish and Swedish registry cohorts show clozapine is associated with lower psychiatric hospitalisation across schizophrenia-spectrum, bipolar disorder and severe depression without increased overall mortality or hospitalisation.

Clozapine and Infection Risk in Schizophrenia: Insights from a Hong Kong Population Study
PsychiatryclozapineInfection Risk
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Clozapine and Infection Risk in Schizophrenia: Insights from a Hong Kong Population Study

By MedXY|Oct 4, 2025

This study reveals an increased risk of infections among schizophrenia patients treated with clozapine compared to olanzapine, highlighting the need for vigilant infection monitoring and preventive care.

Semaglutide for Weight Management in Clozapine-Treated Schizophrenia: Results from the COaST Phase 2 RCT in Australia
Clinical Updatesclinical trialclozapine

Semaglutide for Weight Management in Clozapine-Treated Schizophrenia: Results from the COaST Phase 2 RCT in Australia

By MedXY|Oct 1, 2025

Semaglutide significantly reduced body weight without impacting psychotic symptoms or clozapine levels in people with schizophrenia and obesity on clozapine therapy.

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