Clostridioides difficile

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Gastroenterologyantibiotic-associated diarrheaClostridioides difficile

Probiotics Cut Clostridioides difficile Risk in Antibiotic-Exposed Patients — Small Benefit, Low Certainty

By MedXY|Dec 18, 2025

A 2025 Cochrane update finds probiotics may halve the relative risk of C. difficile-associated diarrhea in antibiotic-treated patients (ARR 1.6%, NNT 65) but evidence is low certainty and applicability varies with baseline risk.

Critical CareClostridioides difficile

Antibiotic Exposure as a Major Risk Factor for Clostridioides difficile Infection: Evidence from a Large Israeli Cohort and Systematic Reviews

By MedXY|Oct 4, 2025

Recent research confirms that antibiotic exposure doubles the risk of hospital-onset Clostridioides difficile infection (CDI), especially in non-carriers, underscoring the central role of antibiotic stewardship and the need for additional p

Clinical UpdatesClostridioides difficile

Fecal Microbiota Transplantation versus Vancomycin in Primary Clostridioides difficile Infection: A Noninferiority Randomized Trial

By MedXY|Sep 30, 2025

FMT is noninferior to vancomycin for primary CDI, with similar cure rates and safety, suggesting it may be a viable first-line therapy.