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Differentiating Allergic Fungal Rhinosinusitis from Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: Insights from Structured Histopathology in a Saudi Cohort

This study delineates distinct clinical, radiographic, laboratory, and histopathologic features separating allergic fungal rhinosinusitis from eosinophilic chronic rhinosinusitis with nasal polyps in a Middle Eastern tertiary-care cohort.

Oct 6, 2026
news

Histopathologic Insights in Chronic Rhinosinusitis Linked to Intranasal Substance Use: Implications for Clinical Management

This study reveals distinct histopathologic features in chronic rhinosinusitis patients with intranasal substance use, highlighting increased neutrophilic inflammation and epithelial remodeling, underscoring the need for targeted clinical a

Sep 23, 2026
news

Validating the Adaptive Sinonasal Outcome Test (SNOT): A Clinically Reliable Tool for Chronic Rhinosinusitis Assessment

The adaptive Sinonasal Outcome Test (SNOT) demonstrates strong validity, reliability, and responsiveness in assessing symptoms and treatment outcomes in chronic rhinosinusitis, correlating well with objective CT imaging and overall health m

Jul 17, 2026
Allergy & Immunology

Bridging Subjective Symptoms and Objective Imaging in Chronic Rhinosinusitis: Impact of an Adaptive Sino-Nasal Outcome Test

A novel adaptive Sino-Nasal Outcome Test (SNOT) yields improved correlation with computed tomography findings in chronic rhinosinusitis, enhancing clinical assessment and differentiation from allergic rhinitis.

Jul 15, 2026
Allergy & Immunology

Gender Differences in Chronic Rhinosinusitis: Insights into Diagnosis and Biomarkers

This study explores how biological sex influences CRS diagnosis and inflammatory biomarkers, revealing sex-specific patterns that could inform personalized treatment.

Oct 24, 2025
Respiratory

MACRO Trial Insights: Endoscopic Sinus Surgery Outperforms Clarithromycin in Chronic Rhinosinusitis Management

The MACRO trial demonstrates that endoscopic sinus surgery significantly improves quality of life in adults with chronic rhinosinusitis, while long-term low-dose clarithromycin shows no added benefit over placebo.

Sep 21, 2025

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