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A pragmatic RCT suggests that exercise following spinal cord injury guidelines may reduce chronic pain intensity, with significant benefits observed in pain interference and coping strategies.
A large Danish study evaluates how mesh placement during incisional hernia repair affects patient-reported outcomes, finding increased foreign body sensation with onlay mesh but no differences in chronic pain or recurrence.
A large nationwide Danish survey reveals that chronic pain and sexual dysfunction are common long-term consequences following groin hernia repair in adolescents, underscoring the need for tailored surgical approaches and specialized care.
This study develops and compares predictive models incorporating claims and patient-reported data to forecast time to first opioid use disorder (OUD) or overdose (OD) among older adults with chronic pain on opioids, identifying key risk fac
Chronic pain conditions significantly elevate the risk of developing dry eye disease, including cases requiring prescription therapy, emphasizing the need for integrated clinical assessment and management.
A large RCT found that adding behavioral therapies to patient-centered opioid tapering did not improve taper success at 12 months, though CBT may reduce adverse effects; complementary digital support programs show feasibility but require fu
Researchers using human stem cell models have discovered that macrophages actively amplify the electrical signals of damaged nerves, driving the spontaneous pain characteristic of neuropathy, offering a new target for non-opioid pain relief
A cross-sectional analysis of the HOPE Consortium Trial reveals that chronic pain in hemodialysis patients is widespread, frequently musculoskeletal and neuropathic, and strongly associated with psychological and sociodemographic factors ra
This study applies machine learning and explainable AI to identify factors associated with chronic pain, psychological distress, and their co-occurrence in Norwegian young adults, highlighting the importance of integrated approaches for ear
A UK cohort study reveals that adolescent dysmenorrhoea increases the risk of chronic pain in adulthood, highlighting the need for early identification and management.
This study investigates the relationship between sleep quality and cognitive function in individuals with chronic primary musculoskeletal pain.
Remote CBT-based interventions, delivered by telehealth or online modules, offer modest but significant improvements in pain and function for individuals with high-impact chronic pain, enhancing access to evidence-based care.
