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Childhood Cancer Survivors

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Dose-Dependent Radiation and Chemotherapy Risks for Colorectal Subsequent Malignancies in Childhood Cancer Survivors: Clinical Implications from a CCSS Analysis

A CCSS analysis of 25,723 five-year childhood cancer survivors shows clear dose-response relationships between colorectum-specific radiation dose, irradiated colorectal volume, several chemotherapy exposures (notably procarbazine, high alky

Dec 10, 2025Sign in to read
Cardiology

Long-Term Risk Factors for Valvular Heart Disease in Childhood Cancer Survivors: Insights from a European Case-Control Study

Heart radiation, anthracyclines, and platinum chemotherapy significantly increase the risk of valvular heart disease decades after childhood cancer treatment, highlighting the need for vigilant, lifelong cardiac monitoring in survivors.

Oct 10, 2025
Oncology

Impact of BMI and Physical Activity on Subsequent Neoplasm Risk in Childhood Cancer Survivors: Insights from the CCSS Cohort

Obesity increases, while higher physical activity decreases, risk of subsequent neoplasms among childhood cancer survivors, highlighting lifestyle intervention potential for cancer prevention.

Aug 23, 2025Sign in to read

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