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CFTR Modulators

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Infectious Diseases

Evolving Impact of Inhaled Antibiotics on Lung Function in Cystic Fibrosis During the CFTR-Modulator Era

This analysis of U.S. CF Foundation registry data reveals that inhaled antibiotics confer lung function benefits primarily in chronic Pseudomonas aeruginosa infections, but their treatment benefit has declined with CFTR modulator use. Risks

Sep 26, 2026
Clinical Updates

Transformative Survival Gains in Cystic Fibrosis: A Population-Level Evaluation of CFTR Modulator Therapy Effectiveness

A large-scale retrospective study using US CFF Registry data reveals that CFTR modulator therapy reduces the hazard of death by 66% over an eight-year period, marking a significant milestone in cystic fibrosis clinical outcomes and life exp

May 14, 2026

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