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Medical and Surgical Treatments for Neurotrophic Keratopathy: What Randomized Trials Tell Us (and What They Don’t)
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Medical and Surgical Treatments for Neurotrophic Keratopathy: What Randomized Trials Tell Us (and What They Don’t)

By MedXY|Dec 16, 2025

A Cochrane review of seven RCTs (494 participants) finds low- to very low-certainty evidence that select medical therapies — notably recombinant human nerve growth factor — may improve corneal re-epithelialization in neurotrophic keratopath

Cenegermin Eye Drops Show High Healing Rates in Chinese Patients with Moderate–Severe Neurotrophic Keratopathy
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Cenegermin Eye Drops Show High Healing Rates in Chinese Patients with Moderate–Severe Neurotrophic Keratopathy

By MedXY|Nov 2, 2025

A prospective phase IV open‑label Chinese study found cenegermin achieved corneal healing in 84.6% of stage 2/3 neurotrophic keratopathy patients at 8 weeks, with durable effects through 56 weeks and an acceptable safety profile.

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