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Neurology

SleepCARE Trial: CBT-I, Not Bright Light Therapy, Improves Insomnia During Breast Cancer Chemotherapy

In the four-arm SleepCARE trial of 219 women receiving breast cancer chemotherapy, brief CBT-I significantly improved insomnia while bright light therapy did not beat sleep hygiene education. Neither helped fatigue, and combining the two added burden without benefit.

Oct 4, 2026Sign in to read
news

Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes

A randomized clinical trial demonstrates that combining high-intensity circuit training (HICT) with sleep health (SH) counseling significantly outperforms mono-interventions in improving sleep efficiency, reducing wakefulness, and enhancing

Feb 23, 2026
Internal Medicine

Low-Dose Amitriptyline vs. CBT-I for Comorbid Insomnia: Statistical Non-Inferiority Meets Clinical Reality

A multicenter trial finds low-dose amitriptyline non-inferior to CBT-I for comorbid insomnia based on a liberal margin. However, CBT-I yielded superior clinical response rates and fewer side effects, reinforcing its status as the gold-stand

Dec 30, 2025Sign in to read
Neurology

Tai Chi as a Long-term Alternative to CBT-I for Chronic Insomnia in Older Adults: A Randomized Non-inferiority Trial

A randomized trial comparing Tai Chi and CBT-I in adults over 50 found that while CBT-I offers faster relief, Tai Chi achieves non-inferior results at 12 months post-intervention, suggesting it is a viable long-term strategy for insomnia ma

Dec 30, 2025
Neurology

Scalable Solutions for Sleep: Converging Evidence from a Nationwide RCT and Meta-Analysis Validates Digital CBT-I

This article analyzes a nationwide decentralized RCT and a systematic meta-analysis to evaluate the efficacy of digital Cognitive Behavioral Therapy for Insomnia (CBT-I), highlighting its role as a scalable, evidence-based first-line treatm

Dec 21, 2025
news

CBT‑I in Cancer Survivors: Small Subjective Gains, Unclear Objective Benefits — What the 2025 Cochrane Review Tells Clinicians

A 2025 Cochrane review of 21 RCTs (2431 participants) finds cognitive behavioural therapy for insomnia (CBT‑I) yields modest improvements in self‑reported insomnia and sleep quality in people with cancer versus inactive controls or aerobic

Dec 16, 2025
Neurology

Acupuncture for Cancer-Related Insomnia: Limited, Low-Certainty Benefits Compared with Sham or No Treatment; Inferior to CBT‑I

A 2025 Cochrane review (5 RCTs, 402 patients, mainly women with breast cancer) finds very low- to moderate-certainty evidence that acupuncture delivers small, uncertain sleep diary benefits versus sham or inactive controls and is probably l

Dec 16, 2025Sign in to read
news

Hiệu quả và Độ chấp nhận của Liệu pháp Hành vi Nhận thức cho Chứng mất ngủ trong Bệnh mãn tính: Một Phân tích tổng hợp Toàn diện

Phân tích tổng hợp này xác nhận rằng liệu pháp hành vi nhận thức cho chứng mất ngủ (CBT-I) là một phương pháp điều trị hiệu quả, được chấp nhận tốt, cải thiện kết quả giấc ngủ ở các bệnh mãn tính đa dạng, với tác dụng phụ tối thiểu và tiềm

Sep 28, 2025
Clinical Updates

Efficacy and Acceptability of Cognitive Behavioral Therapy for Insomnia in Chronic Disease: A Comprehensive Meta-Analysis

This meta-analysis confirms that cognitive behavioral therapy for insomnia (CBT-I) is an effective, well-accepted treatment improving sleep outcomes across diverse chronic diseases, with minimal adverse effects and potential for broad clini

Sep 28, 2025

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