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Anesthesiology

Evaluating Cardiac Index-Guided Hemodynamic Therapy in High-Risk Abdominal Surgery: Insights from the PELICAN Trial

The PELICAN trial found that individualized cardiac index-guided intraoperative hemodynamic therapy did not reduce major postoperative complications compared to routine care in high-risk major abdominal surgery patients.

Oct 26, 2026
Cardiology

Beyond Congestion: The Wet-Cold Phenotype Drives Mortality in Obese HFpEF

A hemodynamic study of 227 HFpEF patients reveals that 34% exhibit a low-output phenotype. This cold status, especially when combined with congestion, significantly increases mortality risk in overweight and obese individuals, highlighting

Dec 29, 2025
Critical Care

A 250‑ml Ultrafiltration Challenge Identifies Patients at Risk of Becoming Preload‑Dependent During CRRT

A randomized cross‑over trial found that a 250‑ml net ultrafiltration challenge reliably identified preload‑independent critically ill patients who became preload‑dependent during continuous renal replacement therapy; a ≥5% calibrated cardi

Nov 7, 2025

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