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capecitabine

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Dermatology

Efficacy and Tolerability of Long-Term Low-Dose Capecitabine for Refractory Cutaneous Field Cancerization: Insights from a Retrospective Cohort Study

This study demonstrates that long-term, low-dose capecitabine significantly reduces keratinocyte carcinoma surgeries in patients with refractory cutaneous field cancerization and is generally well tolerated, offering a promising therapeutic

Oct 22, 2026
news

A Decadel Leap: TCX Regimen Outperforms Standard TAC in 10-Year Survival for High-Risk HER2-Negative Breast Cancer

A 10-year randomized trial reveals that replacing anthracyclines with capecitabine (TCX) significantly improves overall survival and reduces toxicity compared to the standard TAC regimen in high-risk, HER2-negative breast cancer patients.

Jan 14, 2026Sign in to read
news

Metronomic Capecitabine Gives Durable 10‑Year DFS Benefit in Early Triple‑Negative Breast Cancer — FOXC1 May Identify Who Benefits

A 10‑year follow‑up of SYSUCC‑001 shows 1 year of metronomic capecitabine after standard adjuvant therapy improved disease‑free survival in early triple‑negative breast cancer; FOXC1 expression emerged as a potential predictive biomarker in

Nov 30, 2025Sign in to read
Clinical Updates

Methylcobalamin Significantly Reduces Severe Hand-Foot Syndrome in HER2 Negative Early Breast Cancer Patients Receiving Capecitabine: Results from a Phase 3 Randomised Trial

Oral methylcobalamin notably decreased the incidence of grade ≥2 hand-foot syndrome in patients with HER2 negative early breast cancer undergoing adjuvant capecitabine treatment, without added safety concerns, improving treatment adherence

Sep 20, 2025
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