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Global Variations in Concurrent Hysterectomy During Risk-Reducing Surgery for BRCA1/2 Carriers: An Integrated Quantitative and Qualitative Analysis

This study reveals significant international differences in concurrent hysterectomy rates during risk-reducing salpingo-oophorectomy among BRCA1/2 variant carriers and explores underlying factors influencing surgical decisions across region

Jul 3, 2026

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Peritoneal Cancer Risk After Risk-Reducing Salpingo-Oophorectomy: The Impact of BRCA Mutational Status and STIC Lesions

This study of 1,351 high-risk women demonstrates that while risk-reducing salpingo-oophorectomy (RRSO) is effective, the presence of serous tubal intraepithelial carcinoma (STIC) at the time of surgery significantly increases the 5-year ris

Mar 15, 2026

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FDA Greenlights Niraparib–Abiraterone–Prednisone for BRCA2‑Mutated Metastatic Castration‑Sensitive Prostate Cancer: Implications and Practical Considerations

The FDA approved once‑daily niraparib plus abiraterone acetate and prednisone for adults with deleterious or suspected deleterious BRCA2‑mutated metastatic castration‑sensitive prostate cancer (CSPC), based on rPFS and interim overall survi

Dec 15, 2025