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Body Weight and Alteplase Efficacy in Acute Ischemic Stroke: Insights from the ENCHANTED Trial
Critical CareENCHANTED trialThrombolysis

Body Weight and Alteplase Efficacy in Acute Ischemic Stroke: Insights from the ENCHANTED Trial

By MedXY|Aug 28, 2026

The ENCHANTED trial post hoc analysis reveals body weight does not alter alteplase dose effectiveness in acute ischemic stroke, but low body weight independently predicts poorer outcomes without increased hemorrhagic risk.

Impact of Chronic Mild Sleep Restriction on Body Weight and Composition: Insights from Pooled Randomized Trials
Diabetes & EndocrinologyAdipositybody weight

Impact of Chronic Mild Sleep Restriction on Body Weight and Composition: Insights from Pooled Randomized Trials

By MedXY|Jul 9, 2026

Prolonged mild sleep restriction of 1.5 hours per night over six weeks leads to modest weight gain, increased adiposity, and elevated leptin levels, highlighting the importance of adequate sleep in weight management and cardiometabolic risk

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