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Evaluating Neurodevelopmental Outcomes Following Intrapartum Azithromycin Administration in Neonates with Birth Asphyxia: Insights from the A-PLUS Follow-Up Study
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Evaluating Neurodevelopmental Outcomes Following Intrapartum Azithromycin Administration in Neonates with Birth Asphyxia: Insights from the A-PLUS Follow-Up Study

By MedXY|Sep 8, 2026

A multicountry follow-up study found no significant improvement in neurodevelopmental outcomes at two years in infants with birth asphyxia whose mothers received a single 2 g oral dose of azithromycin during labor versus placebo.

Mass Azithromycin Administration in Malian Infants Shows No Mortality Benefit: A Large-Scale Randomized Trial
Infectious Diseasesazithromycin
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Mass Azithromycin Administration in Malian Infants Shows No Mortality Benefit: A Large-Scale Randomized Trial

By MedXY|Oct 25, 2025

A large randomized trial in Mali demonstrated that mass azithromycin administration to infants aged 1–11 months did not reduce mortality compared to placebo, challenging previous findings in sub-Saharan Africa.

Does Treating Older Siblings Enhance the Impact of Azithromycin on Infant Survival? Insights from a Cluster-Randomized Trial in Niger
Clinical Updatesazithromycinmass drug administration

Does Treating Older Siblings Enhance the Impact of Azithromycin on Infant Survival? Insights from a Cluster-Randomized Trial in Niger

By MedXY|Oct 1, 2025

Mass azithromycin administration to both infants and older children reduced infant mortality more than treating infants alone, with potential spillover benefits from treating older siblings.

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