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AQP4-IgG

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Neurology

Enhancing Diagnosis of AQP4-IgG+ NMOSD Myelitis: The Role of Novel and Established Spinal MRI Signs

This article evaluates spinal MRI features in AQP4-IgG+ NMOSD myelitis, highlighting the diagnostic specificity of bright spotty lesions, the double-contoured LETM sign, and sagittal ring enhancement for differentiating NMOSD from other mye

Sep 25, 2026
Clinical Updates

Age at Onset and Clinical Trajectory in AQP4-IgG NMOSD: Decoupling Relapse Risk from Disability Accrual

This review analyzes how age at onset influences NMOSD, revealing that while relapse risk remains constant across age groups, older onset significantly accelerates disability progression, necessitating early high-efficacy therapy.

Mar 6, 2026

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