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Gastroenterology

Short-Term Antibiotic Success but Long-Term Challenges in Pouchitis: Insights into Microbial Strain Dynamics and Virulence Re-Emergence

Antibiotic treatment transiently improves pouchitis by suppressing exotoxin-producing bacteria, but resistant strains quickly re-emerge, driving relapse; targeted microbial approaches are needed for sustained remission.

Sep 13, 2026Sign in to read
Gastroenterology

Precision Genomics Outperforms Empirical Approaches in Managing Drug-Resistant Helicobacter pylori

A global genomic study of Helicobacter pylori reveals that mutations in 23S rRNA and gyrA predict antibiotic resistance with 100% sensitivity, signaling the end of empirical therapy in favor of genotype-based personalized treatment.

Dec 29, 2025
Critical Care

Selective Decontamination of the Digestive Tract in ICU Ventilated Patients: Impact on Mortality and Microbial Ecology

A large international trial found that selective decontamination of the digestive tract (SDD) during mechanical ventilation did not reduce hospital mortality but decreased bloodstream infections and antibiotic-resistant organisms, with no c

Oct 31, 2025
Clinical Updates

Corynebacterium diphtheriae Outbreak among Migrants in Europe: Clinical, Epidemiologic, and Microbiologic Insights

A multicountry outbreak of diphtheria among migrants in Europe raised concerns about cutaneous and respiratory disease, cross-border spread, and emerging antibiotic resistance. Genomic analysis revealed multiclonal transmission and resistan

Aug 1, 2025
Infectious Diseases

The Invisible Enemy: Are Superbugs Winning the War on Antibiotics?

Antibiotic resistance is growing worldwide, threatening our ability to treat common infections. Discover the science, misconceptions, and what we can all do to combat superbugs.

Jul 25, 2025Sign in to read
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