anthracycline cardiotoxicity

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Anthracycline Cardiotoxicity Exacerbated by Metabolic Stress in Pressure-Overloaded Hearts: Mechanistic Insights and Clinical Implications

Left ventricular pressure overload induces metabolic vulnerability that heightens susceptibility to anthracycline cardiotoxicity, revealing a critical need for targeted preventive strategies in patients with hypertension or valvular disease

Sep 21, 2026Sign in to read

Cardiology

Plasma Biomarkers CPVL and PIGR Predict Anthracycline-Induced Cardiotoxicity in Hematologic Cancer Patients

Baseline plasma levels of CPVL and PIGR correlate with anthracycline-induced systolic dysfunction, offering potential early biomarkers for cardiotoxicity in hematologic malignancy patients undergoing chemotherapy.

Aug 28, 2026Sign in to read

Cardiology

Atorvastatin Preserves Aortic Elasticity During Anthracycline Chemotherapy: Secondary Analysis of STOP‑CA

In a secondary analysis of the randomized STOP‑CA trial, atorvastatin 40 mg daily attenuated anthracycline‑associated increases in aortic stiffness measured by CMR pulse wave velocity, suggesting vascular protection and a potential strategy

Nov 25, 2025